The Henry Wellcome Building for Nuclear Magnetic Resonance (NMR) is the UK’s largest biomolecular NMR facility.
It provides academic and industrial users with open access to seven NMR spectrometers operating at 500-900 MHz, six cryogenic probes, and high-throughput autosamplers.
Researchers from across the world are invited to study the 3D structures and interactions of proteins, nucleic acids, carbohydrates, lipids and metabolites at the HBW-NMR; a national resource based in Birmingham, providing scientists with insights into the molecular basis of human health, cancer progression and infectious diseases.
Our goal is to provide researchers with the world’s best NMR technologies and services for the study of biomolecular structures, dynamics and interactions.
The aim of the facility is to:
- Provide state-of-the-art NMR services for internationally competitive biomedical research in fields including structural biology, signal transduction, membrane trafficking, cancer mechanisms and metabolic profiling of human disease,
- Develop and make available next generation NMR technologies including high-field magnets, cryogenic probes, fast methods and high throughput autosamplers in order to open new avenues of scientific investigation
- Support the NMR needs of collaborative research groups and global initiatives focusing on UK and European priority areas including structural proteomics, biomarker identification and drug discovery.
The Henry Wellcome Building for Biomolecular Nuclear Magnetic Resonance Spectroscopy is a national facility funded by the Wellcome Trust, the Higher Education Funding Council for England and the University of Birmingham.
NMR involves the detection of radiofrequency signals from several types of atoms placed in a magnetic field. It is used to reveal the three dimensional structures of proteins, which are composed of thousands of atoms uniquely arranged in space in order to perform a specific biological function within an organism.