World first: gene therapy trial for rare disease patient

A patient at BHP’s Queen Elizabeth Hospital Birmingham (QEHB) has become the first person in the world to take part in a pioneering gene therapy trial for his rare disease. Simon Smith, 45, was diagnosed with Ornithine Transcarbamylase (OTC) deficiency as a teenager.   Although he defied medical expectations by living a full life in … Continue reading “World first: gene therapy trial for rare disease patient”

Genome sequencing during pregnancy identifies developmental disorders

Research carried out in collaboration with BHP founder member the University of Birmingham has found that genetic testing improves the diagnoses of abnormalities in developing babies that are picked up during ultrasound scans. The research, published today in The Lancet, was carried out by the University’s Institute of Metabolism and Systems, Wellcome Sanger Institute, University of … Continue reading “Genome sequencing during pregnancy identifies developmental disorders”

Top award for translational biomedical researcher

A BHP clinician scientist and hepatologist Dr Ye Htun Oo has been awarded £1.7 million to fund translational biomedical research into autoimmune liver diseases. The Sir Jules Thorn Award for Biomedical Research is a single grant of up to £1.7 million awarded by the Sir Jules Thorn Charitable Trust. The Trust’s main objective is to fund translational research … Continue reading “Top award for translational biomedical researcher”

Biomarkers identified to help diagnose heart condition

Researchers at BHP founder member the University of Birmingham have found two biomarkers that could be used to identify a heart condition known as atrial fibrillation in patients who have three ‘clinical risks’. Atrial fibrillation is the most common heart rhythm disturbance, affecting around 1.6 million people in the UK. Those with atrial fibrillation may … Continue reading “Biomarkers identified to help diagnose heart condition”

Birmingham to lead ground-breaking research into patient experience of cell therapies

Birmingham health researchers, with industry partners including health technology companies Dignio and Datatrial, have been awarded £1.1 million by UK Research & Innovation (UKRI)’s Innovate UK, to investigate patients’ experience of cell and gene therapies. The funding has been provided as part of the Industrial Strategy Challenge Fund’s Medicines Manufacturing programme. Cell and gene therapies … Continue reading “Birmingham to lead ground-breaking research into patient experience of cell therapies”