12-week delay for second Pfizer vaccine significantly increases antibody responses in older people

Antibody response in people aged over 80 is three-and-a-half times greater in those who have the second dose of the Pfizer COVID-19 vaccine after 12 weeks compared to those who have it at a three-week interval, finds a new study led by BHP founder-member the University of Birmingham in collaboration with Public Health England. The … Continue reading “12-week delay for second Pfizer vaccine significantly increases antibody responses in older people”

Agents that target viral RNA could be basis for next-gen anti-virals

A new approach to tackling viruses by targeting the ‘control centre’ in viral RNA could lead to broad spectrum anti-viral drugs and provide a first line of defence against future pandemics, according to new research at BHP founder-member the University of Birmingham. In a new study, published in Angewandte Chemie, researchers have shown how this approach … Continue reading “Agents that target viral RNA could be basis for next-gen anti-virals”

Investigating immune response to SARS-CoV-2 infection in patients with antibody deficiencies

A new study being led by BHP founder-members the University of Birmingham and University Hospitals Birmingham NHS Foundation Trust – working with University College London – aims to explore the immune response to natural COVID-19 infection and vaccination in patients with antibody deficiency. Funded by UK Research and Innovation (UKRI), ‘COVID infection in patients with Antibody … Continue reading “Investigating immune response to SARS-CoV-2 infection in patients with antibody deficiencies”

Study outlines mechanism behind rare blood clots linked to COVID-19 vaccine

New research carried out in collaboration with researchers from Birmingham Health Partners has characterised a rare COVID-19 vaccine-induced syndrome which causes blood clots. The research has identified fundamental laboratory and clinical characteristics, ensuring that patients are given the correct treatment approach. Published in the New England Journal of Medicine, the research describes rare cases of blood … Continue reading “Study outlines mechanism behind rare blood clots linked to COVID-19 vaccine”

Simple oral hygiene could help reduce COVID-19 severity

COVID-19 could pass into people’s lungs from saliva with the virus moving directly from mouth to bloodstream – particularly if individuals are suffering from gum disease, according to new research. Evidence shows that blood vessels of the lungs, rather than airways, are affected initially in COVID-19 lung disease with high concentrations of the virus in … Continue reading “Simple oral hygiene could help reduce COVID-19 severity”