Birmingham leads the way in delivery of a new advanced therapy in uveal melanoma

BHP founder-member University Hospitals Birmingham is the first site in the UK to treat a uveal melanoma patient with the new therapy Tebentafusp outside a clinical trial. Uveal melanoma is a rare cancer situated within the eye. This initiative is being led by Dr Leila Khoja, Immunotherapy lead for the Birmingham Experimental Cancer Medicine Centre (ECMC) and … Continue reading “Birmingham leads the way in delivery of a new advanced therapy in uveal melanoma”

SPIRIT-PRO extension: guidelines for inclusion of patient-reported outcomes in protocols of clinical trials

Patient Reported Outcomes (PROs) can provide valuable evidence on the impact of disease and treatment on patients’ symptoms, function and quality of life. High-quality PRO data from trials can inform clinical care, regulatory decisions and health policy. However, problems such as poor data collection, analysis, reporting and interpretation often reduce or negate their value. This … Continue reading “SPIRIT-PRO extension: guidelines for inclusion of patient-reported outcomes in protocols of clinical trials”

Flagship Cancer Research UK precision medicine trial highlights the need for a new approach in treating genomically complicated cancers

A pioneering lung cancer study, led by the University of Birmingham’s Cancer Research UK Clinical Trials Unit, has highlighted important factors that will need to be considered in the next wave of precision medicine studies particularly in treating genomically complicated cancers. Published in Nature, the National Lung Matrix Trial (NLMT) is the world’s largest precision … Continue reading “Flagship Cancer Research UK precision medicine trial highlights the need for a new approach in treating genomically complicated cancers”

Birmingham patient among first to receive COVID-19 convalescent plasma

One of the first people to receive COVID-19 convalescent plasma has spoken about their experience and urged people to donate. Ahmed Bhayat from Handsworth in Birmingham, was one of the first people in the UK to receive a transfusion of convalescent plasma, while he was fighting for his life in the critical care unit at … Continue reading “Birmingham patient among first to receive COVID-19 convalescent plasma”

CAR-T success for UHB patient

A patient at the Queen Elizabeth Hospital Birmingham (QEHB) has become the first in the Midlands to have a successful CAR-T cell therapy, for treatment of her cancer. Sophie Wheldon, aged 21, was diagnosed with leukaemia in June 2018. She went on to receive an unrelated donor stem cell transplant in November but the disease … Continue reading “CAR-T success for UHB patient”