Flagship Cancer Research UK precision medicine trial highlights the need for a new approach in treating genomically complicated cancers

A pioneering lung cancer study, led by the University of Birmingham’s Cancer Research UK Clinical Trials Unit, has highlighted important factors that will need to be considered in the next wave of precision medicine studies particularly in treating genomically complicated cancers. Published in Nature, the National Lung Matrix Trial (NLMT) is the world’s largest precision … Continue reading “Flagship Cancer Research UK precision medicine trial highlights the need for a new approach in treating genomically complicated cancers”

Birmingham patient among first to receive COVID-19 convalescent plasma

One of the first people to receive COVID-19 convalescent plasma has spoken about their experience and urged people to donate. Ahmed Bhayat from Handsworth in Birmingham, was one of the first people in the UK to receive a transfusion of convalescent plasma, while he was fighting for his life in the critical care unit at … Continue reading “Birmingham patient among first to receive COVID-19 convalescent plasma”

CAR-T success for UHB patient

A patient at the Queen Elizabeth Hospital Birmingham (QEHB) has become the first in the Midlands to have a successful CAR-T cell therapy, for treatment of her cancer. Sophie Wheldon, aged 21, was diagnosed with leukaemia in June 2018. She went on to receive an unrelated donor stem cell transplant in November but the disease … Continue reading “CAR-T success for UHB patient”

Integration in sight: multidisciplinary team tackles vision loss

The challenge Injuries to the surface of the eye – as a result of burns, infections, inflammation, trauma and surgery – are a leading cause of sight loss. Despite this, there are few therapeutic options to modify, minimise or reverse scarring to maintain corneal transparency and visual function, and these are not always effective. With … Continue reading “Integration in sight: multidisciplinary team tackles vision loss”

Field genomics: portable sequencer tracks infectious disease outbreaks

The challenge Conventional genome sequencing technologies are difficult to deploy in developing countries, particularly where continuous power is not always available and when access to cold chains, lab space and trained personnel is often limited. In addition, some genome sequencer instruments, such as those using optical readings (e.g. the Illumina platform), require precise microscope alignment … Continue reading “Field genomics: portable sequencer tracks infectious disease outbreaks”