12-week delay for second Pfizer vaccine significantly increases antibody responses in older people

Antibody response in people aged over 80 is three-and-a-half times greater in those who have the second dose of the Pfizer COVID-19 vaccine after 12 weeks compared to those who have it at a three-week interval, finds a new study led by BHP founder-member the University of Birmingham in collaboration with Public Health England. The … Continue reading “12-week delay for second Pfizer vaccine significantly increases antibody responses in older people”

Better treatment for miscarriage patients is also more cost effective

A new drug combination that is better at treating miscarriage is also more cost effective than current standard NHS treatment, finds a new study led by BHP founder-member the University of Birmingham and Tommy’s National Centre for Miscarriage Research. A previous study by the same team and published in The Lancet in August last year, found that … Continue reading “Better treatment for miscarriage patients is also more cost effective”

Revolutionising diagnosis and treatment of life-threatening post-partum haemorrhage

Post-partum haemorrhage (PPH) accounts for 27% of all maternal deaths worldwide, according to the World Health Organization (WHO). The burden of PPH disproportionately affects mothers from low- and middle-income countries, which account for 86% of all maternal deaths. PPH is defined as blood loss from the genital tract of 500 ml or more within 24 hours of … Continue reading “Revolutionising diagnosis and treatment of life-threatening post-partum haemorrhage”

Agents that target viral RNA could be basis for next-gen anti-virals

A new approach to tackling viruses by targeting the ‘control centre’ in viral RNA could lead to broad spectrum anti-viral drugs and provide a first line of defence against future pandemics, according to new research at BHP founder-member the University of Birmingham. In a new study, published in Angewandte Chemie, researchers have shown how this approach … Continue reading “Agents that target viral RNA could be basis for next-gen anti-virals”

Investigating immune response to SARS-CoV-2 infection in patients with antibody deficiencies

A new study being led by BHP founder-members the University of Birmingham and University Hospitals Birmingham NHS Foundation Trust – working with University College London – aims to explore the immune response to natural COVID-19 infection and vaccination in patients with antibody deficiency. Funded by UK Research and Innovation (UKRI), ‘COVID infection in patients with Antibody … Continue reading “Investigating immune response to SARS-CoV-2 infection in patients with antibody deficiencies”