Why is COVID-19 life threatening for some, but not others?

With the SARS-CoV-2 pandemic still holding the world in its grip, identifying how our immune system responds to the virus is critical to understanding the unknowns surrounding COVID-19. The human immune system is extremely complex but understanding of how it reacts during and after infection with SARS-CoV-2 is critical to our ability to control the … Continue reading “Why is COVID-19 life threatening for some, but not others?”

World-first: UHB recruits patient to pioneering gene therapy trial

The first person to take part in a industry-sponsored BMN 307 gene therapy study for Phenylketonuria (PKU) has been recruited at BHP founder-member University Hospitals Birmingham NHS Foundation Trust (UHB). The PHEARLESS study aims to investigate if a gene therapy could help people with phenylketonuria (PKU), a rare genetic disease that makes it difficult for … Continue reading “World-first: UHB recruits patient to pioneering gene therapy trial”

New online research database will boost battle against COVID-19

Researchers around the world can tap into a new inter-disciplinary online database of COVID-19 research – www.covidcorpus.org – allowing them to search for new partners, resources and funding to boost the global battle against the virus. Launched today, the international open-access database for ongoing research activity COVID CORPUS aims to encourage collaboration and reduce duplication between researchers … Continue reading “New online research database will boost battle against COVID-19”

National Arthritis Week: treating the causes of inflammatory disease – not just symptoms

Birmingham is tackling inflammatory diseases like arthritis in partnership with the University of Oxford, through the Arthritis Therapy Acceleration Programme (A-TAP).  A-TAP is an initiative which aims to support and develop novel treatments for arthritis based on the underlying causes of inflammatory disease – moving away from a traditional ‘organ-based, speciality-focussed’ approach to a process-driven, … Continue reading “National Arthritis Week: treating the causes of inflammatory disease – not just symptoms”

Reducing deaths in childbirth: new trial now recruiting across Africa and Asia

Researchers based at the University of Birmingham are starting a ground-breaking maternal health trial across 80 hospitals in South Africa, Kenya, Nigeria, Tanzania and Sri Lanka. The trial, called the E-MOTIVE study, aims to reduce severe bleeding after birth and ultimately reduce maternal deaths and complications due to bleeding by 25%. Excessive bleeding after childbirth … Continue reading “Reducing deaths in childbirth: new trial now recruiting across Africa and Asia”